This important amino acid helps block fat storage and reverse weight gain through its various roles in the body. Biotin can be used for metabolism issues such as biotinidase, holocarboxylase synthetase, and isolated carboxylase enzyme deficiencies due to its essential role in the metabolism of fatty acids, glucose, and amino acids.
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Free biotin is then absorbed in the small intestine. This creates biocytin, which is then cleaved by biotinidase into free biotin and lysine. Gastrointestinal enzymes break down ingested biotin via proteolysis. It is mostly protein-bound in foods such as organ meats, eggs, nuts, and soybeans. Biotin functions as an essential cofactor for five carboxylases that catalyze steps in fatty acid, glucose, and amino acid metabolism. It is found primarily in liver, kidney, and muscle. It is important for the metabolism of carbohydrates, fats, and amino acids. Radiolabeled biotin is used for pretargeted radioimmunotherapy of cancerous tumors.īiotin is found naturally in some foods and used as a dietary supplement. Biotin is found in many cosmetics products. It has also been used in pregnancy, hemodialysis, and peritoneal dialysis, as biotin deficiency is more likely in these situations. As a dietary supplement, biotin has been promoted to be useful in the treatment of hair and nail problems, cradle cap (seborrheic dermatitis) in phenylketonuria patients, biotinidase deficiency, diabetes, peripheral neuropathy, candida infections, and high cholesterol. Sources of biotin include organ meats, eggs, fish, seeds, and nuts. Mammals must consume biotin to replenish stores.
It is also an important factor in histone modifications, gene regulation, and cell signaling. Biotin also helps to regulate signals sent by cells and the activity of genes.īiotin (vitamin H coenzyme R classified as a B vitamin) is a dietary component that is important for the metabolism of carbohydrates, fats, and amino acids. It plays a vital role in assisting enzymes to break down fats, carbohydrates, and proteins in food. Biotin is a water-soluble B vitamin found naturally in some foods and also in supplements.
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